SUMMARY The group I capsular polysaccharides (CPS) are assembled through the Wzy-dependent pathway that involves Wza, Wzb and Wzc proteins. CPS has been characterized as a virulence factor that confers antimicrobial resistance in Escherichia coli (E. coli).
UJEMI+ Papers
Deletion of the capsule phosphatase gene wzb renders Escherichia coli strain K30 sensitive to the antibiotic nitrofurantoin.
Wednesday, September 5, 2018
Volume 4
Fall 2017 / Winter 2018
Complementation of ompF Into ΔompCΔompF Escherichia coli Confers Increased Sensitivity To SDS-EDTA Treatment
Wednesday, September 5, 2018
Volume 4
Fall 2017 / Winter 2018
SUMMARY The outer membrane (OM) of gram negative bacteria contributes to inherent antibiotic resistance as well as protection against toxins.
Plasmid-Mediated Overexpression of AcrS May Decrease Kanamycin Resistance in Escherichia coli
Wednesday, September 5, 2018
Volume 4
Fall 2017 / Winter 2018
SUMMARY Escherichia coli encodes efflux pumps that confer resistance to antimicrobial compounds. Previous studies have shown that efflux pumps AcrAB and AcrEF have similar structures and functions, and may be repressed by homologous transcriptional repressors.
Plasmid-mediated complementation of wza restores erythromycin susceptibility in Escherichia coli K30 strain CWG281
Wednesday, September 5, 2018
Volume 4
Fall 2017 / Winter 2018
SUMMARY Group 1 capsules are recognized as virulence determinants in bacterial pathogens of humans and animals. They enhance virulence by conferring resistance to phagocytosis and increasing adherence to host tissues.
The effects of the artificial sweetener sucralose on the gut bacteria Escherichia coli and Enterobacter aerogenes
Saturday, January 13, 2018
Volume 3
Fall 2017 / Winter 2018
Recent evidence suggests that the gut microbiome may be altered by the intake of artificial sweeteners. The goal of this study was to examine the effects of sucralose, an artificial sweetener, on two gut bacteria; Enterobacter aerogenes and Escherichia coli.
O16 Serotype O Antigen Expression in Escherichia coli K-12 May Confer Resistance Against T4 Bacteriophage Infection by Preventing Adsorption
Friday, November 17, 2017
Volume 3
Fall 2016 / Winter 2017
T4 bacteriophage infection of Escherichia coli strain K-12 has been well established as a model for studying virus–host interactions. Lipopolysaccharide (LPS) structure has been shown to be key for such interactions and can impact T4 bacteriophage adsorption and infection. Recently, Chiu et al.
Deletion of AcrS Results in Increased Expression of acrE and Confers an Increase in Kanamycin Resistance in Escherichia coli BW25113
Thursday, July 13, 2017
Volume 3
Fall 2016 / Winter 2017
Escherichia coli bacteria contain numerous efflux pumps that are responsible for intrinsic resistance to antimicrobial compounds. Previous studies have shown that the efflux pumps AcrAB and AcrEF are similar in structure and may be regulated with enzymes that have homologous functions.
Characterizing the Antibacterial Properties and Transcriptional Alterations Induced by Lemongrass oil in Staphylococcus aureus
Thursday, July 13, 2017
Volume 3
Fall 2016 / Winter 2017
Essential oils have risen in popularity as “all natural” alternatives used to treat a myriad of conditions.
Macrolide Structures Can Confer Differential Susceptibility in Escherichia coli K30 Deletions of Group 1 Capsule Assembly Genes
Thursday, July 13, 2017
Volume 3
Fall 2016 / Winter 2017
The Wzy-dependent biosynthesis system in Escherichia coli K30 is responsible for the assembly and transport of extracellular capsule polysaccharides.
Escherichia coli O Antigen Serotype O16 Is a Restriction Factor for Bacteriophage T4 Infection
Thursday, July 13, 2017
Volume 3
Fall 2016 / Winter 2017
The infection of Escherichia coli by bacteriophage T4 has long been investigated, providing key insights into viral life cycles, genetics, and phage therapy to combat bacterial disease.